Free-Radical-Induced DNA Damage and Its Repair

Author: Clemens Sonntag

Publisher: Springer Science & Business Media

ISBN: 3540305920

Category: Science

Page: 523

View: 8975


The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the cell’s various repair enzymes. Kevin Prise (Cancer Campaign, Gray Laboratory, L- don) was so kind to agree to write this part. However, an adequate description of this strongly expanding area would have exceeded the allocated space by much, and this section had to be omitted. The directors of the Max-Planck-Institut für Strahlenchemie (now MPI für Bioanorganische Chemie), Karl Wieghardt and Wolfgang Lubitz, kindly allowed me to continue to use its facilities after my retirement in 2001. Notably, our - brarian, Mrs. Jutta Theurich, and her right-hand help, Mrs. Rosemarie Schr- er, were most helpful in getting hold of the literature. I thank them very much. Without their constant help, this would have been very difficult indeed.

Radical Puritans in England 1550 - 1660

Author: R.J. Acheson

Publisher: Routledge

ISBN: 1317880706

Category: History

Page: 120

View: 2994


This study of religious tensions in Early Modern England explores the different religious separatist movements between 1550-1660. It describes the development of radical sectarianism during the reign of Charles I and explores why the unity of radical cause was shattered following the restoration of the monarchy in 1660.

Radical Sensations

Author: Shelley Streeby

Publisher: Duke University Press

ISBN: 0822395541

Category: History

Page: 352

View: 6129


The significant anarchist, black, and socialist world-movements that emerged in the late nineteenth century and early twentieth adapted discourses of sentiment and sensation and used the era's new forms of visual culture to move people to participate in projects of social, political, and economic transformation. Drawing attention to the vast archive of images and texts created by radicals prior to the 1930s, Shelley Streeby analyzes representations of violence and of abuses of state power in response to the Haymarket police riot, of the trial and execution of the Chicago anarchists, and of the mistreatment and imprisonment of Ricardo and Enrique Flores Magón and other members of the Partido Liberal Mexicano. She considers radicals' reactions to and depictions of U.S. imperialism, state violence against the Yaqui Indians in the U.S.-Mexico borderlands, the failure of the United States to enact laws against lynching, and the harsh repression of radicals that accelerated after the United States entered the First World War. By focusing on the adaptation and critique of sentiment, sensation, and visual culture by radical world-movements in the period between the Haymarket riots of 1886 and the deportation of Marcus Garvey in 1927, Streeby sheds new light on the ways that these movements reached across national boundaries, criticized state power, and envisioned alternative worlds.

Radical Heroes

Author: Diana Coben

Publisher: Routledge

ISBN: 1135586462

Category: Education

Page: 280

View: 2003


First Published in 1998. Routledge is an imprint of Taylor & Francis, an informa company.

Radical Social Work Today

Author: Michael Lavalette

Publisher: Policy Press

ISBN: 1847428177

Category: Social Science

Page: 236

View: 9641


To celebrate the 35th anniversary of the seminal text Radical Social Work (1975), this volume has been compiled to explore the radical tradition within social work and assess its legacy, relevance and prospects. It is essential reading for undergraduate and postgraduates studying social work, as well as social work academics and researchers.

Radical Chapters

Author: Michael Doyle

Publisher: Syracuse University Press

ISBN: 0815650833

Category: Biography & Autobiography

Page: 428

View: 7599


Long a hub for literary bohemians, countercultural musicians, and readers interested in a good browse, Kepler's Books and Magazines is one of the most well-known independent bookstores in American history. When owner Roy Kepler opened the store in 1955 he changed the book industry forever as a pioneer in the "paperback revolution." The notion of selling texts in inexpensive paperbound volumes was revolutionary in the publishing trade and Kepler's focus on stocking these inexpensive books put him at the forefront of the movement. Paperback-selling was not the only revolution Kepler supported, however. In Radical Chapters, Doyle sheds light on Kepler’s remarkable contributions not only to the book industry but also to pacifism. Recalling the tumultuous politics of the last century, he highlights Kepler’s achievements in advocating radical pacifism during World War II, anti-nuclear activism during the Cold War era, and the anti-Vietnam War movement. During those decades, Kepler’s Books played an integral role, creating a community and space to exchange ideas for such notable figures as Jerry Garica, Joan Baez, and Stewart Brand. Doyle’s fascinating chronicle captures the man who inspired that community and offers a moving tribute to his legacy.

Radical Ecopsychology, Second Edition

Author: Andy Fisher,David Abram

Publisher: SUNY Press

ISBN: 1438444761

Category: Nature

Page: 385

View: 1989


Expanded new edition of a classic examination of the psychological roots of our ecological crisis.

Radical Markets

Author: Eric A. Posner,E. Glen Weyl

Publisher: Princeton University Press

ISBN: 0691196974

Category: Business & Economics

Page: 384

View: 897


Revolutionary ideas on how to use markets to achieve fairness and prosperity for all Many blame today's economic inequality, stagnation, and political instability on the free market. The solution is to rein in the market, right? Radical Markets turns this thinking on its head. With a new foreword by Ethereum creator Vitalik Buterin and virtual reality pioneer Jaron Lanier as well as a new afterword by Eric Posner and Glen Weyl, this provocative book reveals bold new ways to organize markets for the good of everyone. It shows how the emancipatory force of genuinely open, free, and competitive markets can reawaken the dormant nineteenth-century spirit of liberal reform and lead to greater equality, prosperity, and cooperation. Only by radically expanding the scope of markets can we reduce inequality, restore robust economic growth, and resolve political conflicts. But to do that, we must replace our most sacred institutions with truly free and open competition—Radical Markets shows how.

Radical Vision

Author: Soyica Diggs Colbert

Publisher: Yale University Press

ISBN: 030025833X

Category: Biography & Autobiography

Page: 320

View: 1254


A captivating portrait of Lorraine Hansberry’s life, art, and political activism--one of O Magazine's best books of April 2021 "Hits the mark as a fresh and timely portrait of an influential playwright."—Publishers Weekly In this biography of Lorraine Hansberry (1930–1965), the author of A Raisin in the Sun, Soyica Diggs Colbert considers the playwright’s life at the intersection of art and politics, with the theater operating as a “rehearsal room for [her] political and intellectual work.” Colbert argues that the success of Raisin overshadows Hansberry’s other contributions, including the writer’s innovative journalism and lesser known plays touching on controversial issues such as slavery, interracial communities, and black freedom movements. Colbert also details Hansberry’s unique involvement in the black freedom struggles during the Cold War and the early civil rights movement, in order to paint a full portrait of her life and impact. Drawing from Hansberry’s papers, speeches, and interviews, this book presents its subject as both a playwright and a political activist. It also reveals a new perspective on the roles of black women in mid-twentieth-century political movements.

Paul Among the Gentiles: A "Radical" Reading of Romans

Author: Jacob P. B. Mortensen

Publisher: Narr Francke Attempto Verlag

ISBN: 3772000754

Category: Religion

Page: 366

View: 3818


This exciting new interpretation of Pauls Letter to the Romans approaches Pauls most famous letter from one of the newest scholarly positions within Pauline Studies: The Radical New Perspective on Paul (also known as Paul within Judaism). As a point of departure, the author takes Pauls self-designation in 11:13 as apostle to the gentiles as so determining for Pauls mission that the audience of the letter is perceived to be exclusively gentile. The study finds confirmation of this reading-strategy in the letters construction of the interlocutor from chapter 2 onwards. Even in 2:17, where Paul describes the interlocutor as someone who calls himself a Jew, it requests to perceive this person as a gentile who presents himself as a Jew and not an ethnic Jew. If the interlocutor is perceived in this way throughout the letter, the dialogue between Paul and the interlocutor can be perceived as a continuous, unified and developing dialogue. In this way, this interpretation of Romans sketches out a position against a more disparate and fragmentary interpretation of Romans.